Venous thromboembolism (VTE) is a leading cause of complication and death for hospitalized patients. Patients who sustain a VTE have approximately twice the length of stay and total inpatient cost as patients who do not.
Prevention of hospital associated VTE (HA-VTE) is a national priority.
Venous blood clots form specifically at the valves, and genetic prevention of clots at these sites requires pulses of reversing flow of blood that current mechanical therapy devices like intermittent compression and foot pumps don’t create.
Direct imaging of human blood flow in response to passive movements has identified that simultaneous foot flexion and compression at specific intervals creates optimal blood flow patterns.